Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 5/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | ACR | P10323 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553650 | 0.96 | RARB (0.57) | MAPTSMN1; SMN2THRBPRSS1ACR | |
| SCHEMBL11546624 | 0.96 | RARB (0.57) | MAPTSMN1; SMN2THRBPRSS1ACR | |
| SCHEMBL3624271 | 0.95 | THRB (0.58) | MAPTSMN1; SMN2THRBPRSS1ACR | |
| SCHEMBL9842392 | 0.95 | THRB (0.58) | MAPTSMN1; SMN2THRBPRSS1ACR | |
| SCHEMBL18434843 | 0.94 | THRB (0.58) | MAPTSMN1; SMN2THRBKMT2ATHRA | |
| SCHEMBL16073026 | 0.94 | THRB (0.58) | MAPTSMN1; SMN2THRBKMT2ATHRA | |
| SCHEMBL15373862 | 0.94 | THRB (0.58) | MAPTSMN1; SMN2THRBKMT2ATHRA | |
| SCHEMBL12125123 | 0.94 | THRB (0.58) | MAPTSMN1; SMN2THRBKMT2ATHRA | |
| SCHEMBL11964524 | 0.94 | THRB (0.58) | MAPTSMN1; SMN2THRBKMT2ATHRA | |
| SCHEMBL13783616 | 0.94 | THRB (0.58) | MAPTSMN1; SMN2THRBKMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194972-A | Microwave phase modulation with liquid crystals | HUGHES AIRCRAFT COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0472403-A2 | Microwave phase modulation with liquid crystals | Hughes Aircraft Company (US) | 1992-02-26 | — | — | EP | disclosed |
| US-4086002-A | Field effect light shutter employing low temperature nematic liquid crystals | HAFFMANN-LA ROCHE INC. (US) | 1978-04-25 | — | — | US | disclosed |