Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3449044 | 0.83 | ALDH1A1 (0.56) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL250441 | 0.82 | KMT2A (0.47) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL9185883 | 0.81 | KMT2A (0.56) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL6829343 | 0.80 | MEN1 (0.45) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL5983525 | 0.80 | LMNA (0.51) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL6489977 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL9474878 | 0.77 | HDAC1 (0.45) | ALDH1A1L3MBTL1KCNK3KCNK9HPGD | |
| SCHEMBL19459312 | 0.77 | KCNJ11 (0.43) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL30625900 | 0.77 | KMT2A (0.50) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL601548 | 0.77 | KMT2A (0.50) | MEN1KMT2APOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236940-A | Administering for treatment of medical conditions associated with the effects of glutamate; glutamate-induced convulsions; schizophrenia; sleep disorders | RHONE-POULENC SANTE (FR) | 1993-08-17 | — | — | US | disclosed |