Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9475583

CCOS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 15/20 0.46
CA1 P00915 14/20 0.46
MMP1 P03956 5/20 0.39
MMP2 P08253 5/20 0.39
MMP9 P14780 5/20 0.39
MMP8 P22894 5/20 0.39
MMP13 P45452 5/20 0.39
F2 P00734 4/20 0.39
PRSS1 P07477 4/20 0.39
PRSS2 P07478 4/20 0.39
PRSS3 P35030 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29126717 0.98 CA2 (0.47) CA2CA1MMP1MMP2MMP9
SCHEMBL16245138 0.98 CA2 (0.47) CA2CA1MMP1MMP2MMP9
SCHEMBL16245193 0.96 CA2 (0.46) CA2CA1MMP1MMP2MMP9
SCHEMBL776622 0.85 CA1 (0.40) CA2CA1
SCHEMBL5072665 0.81 CA1 (0.40) CA2CA1
SCHEMBL20237404 0.80 CA2 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL20237401 0.80 CA2 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL27641892 0.80 CA2 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL27641894 0.80 CA2 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL27641979 0.80 CA2 (0.33) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5094895-A Expanded PTFE, perfluoro ion exchange resin, electrolytic cell filter W. L. GORE & ASSOCIATES, INC. 1992-03-10 US claimed
EP-0470186-A1 A COMPOSITE, POROUS DIAPHRAGM W.L. GORE & ASSOCIATES, INC. (US) 1992-02-12 EP claimed
WO-1990013593-A1 A COMPOSITE, POROUS DIAPHRAGM W.L. GORE & ASSOCIATES, INC. (US) 1990-11-15 WO claimed
US-4664763-A ELECTROLYSIS M&T CHEMICALS INC. (US) 1987-05-12 US claimed
US-5183545-A Multilayer structure of polytetrafluoroethylene; hydrophilic coating of perfluoro ion exchange polymer; filters W. L. GORE & ASSOCIATES, INC. 1993-02-02 US disclosed
US-5094895-A Expanded PTFE, perfluoro ion exchange resin, electrolytic cell filter W. L. GORE & ASSOCIATES, INC. 1992-03-10 US disclosed
EP-0470186-A1 A COMPOSITE, POROUS DIAPHRAGM W.L. GORE & ASSOCIATES, INC. (US) 1992-02-12 EP disclosed
WO-1990013593-A1 A COMPOSITE, POROUS DIAPHRAGM W.L. GORE & ASSOCIATES, INC. (US) 1990-11-15 WO disclosed
EP-0225888-A4 PROCESS FOR STRIPPING NICKEL OR NICKEL-IRON ALLOY PLATING IN A CHROMIC ACID SOLUTION. M & T CHEMICALS INC (US) 1987-09-02 EP disclosed
EP-0225888-A1 PROCESS FOR STRIPPING NICKEL OR NICKEL-IRON ALLOY PLATING IN A CHROMIC ACID SOLUTION M & T CHEMICALS, INC. (US) 1987-06-24 EP disclosed
US-4664763-A ELECTROLYSIS M&T CHEMICALS INC. (US) 1987-05-12 US disclosed
WO-1986006763-A1 PROCESS FOR STRIPPING NICKEL OR NICKEL-IRON ALLOY PLATING IN A CHROMIC ACID SOLUTION M&T CHEMICALS INC. (US) 1986-11-20 WO disclosed