SCHEMBL9475704

SCHEMBL9475704

CP1(=O)Oc2ccccc2C(=O)P(C)(=O)Oc2ccccc2C1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
PKM P14618 1/20 0.36
TDP1 Q9NUW8 3/20 0.36
ALOX15 P16050 2/20 0.36
TYMS P04818 1/20 0.35
KDM4E B2RXH2 6/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CDC25B P30305 3/20 0.33
MAPK1 P28482 2/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 3/20 0.32
LMNA P02545 3/20 0.32
MAOA P21397 3/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
BLM P54132 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CES2 O00748 1/20 0.32
APAF1 O14727 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822718 0.78 HSP90AA1 (0.33) TSHRPKMTDP1ALOX15TYMS
SCHEMBL822893 0.78 HSP90AA1 (0.33) TSHRPKMTDP1ALOX15TYMS
SCHEMBL16491434 0.78 HSP90AA1 (0.33) TSHRPKMTDP1ALOX15TYMS
SCHEMBL9474982 0.77 DHODH (0.35) TSHRTYMSKDM4EMEN1KMT2A
SCHEMBL9475207 0.76 PKM (0.34) TSHRPKMTDP1ALOX15KDM4E
SCHEMBL16082355 0.76 HSP90AA1 (0.38) TSHRPKMTDP1ALOX15TYMS
SCHEMBL22429045 0.70
SCHEMBL29598331 0.69 ABCG2 (0.35) TSHRPKMLMNAMAOASMN1; SMN2
SCHEMBL2169864 0.69 ABCG2 (0.35) TSHRPKMLMNAMAOASMN1; SMN2
SCHEMBL9848180 0.67 HSP90AA1 (0.38) TSHRPKMTDP1ALOX15TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5214179-A Photoinitiators HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-25 US disclosed