Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830734 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL242968 | 0.82 | HPGD (0.50) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL30536501 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL11131095 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL3478281 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL9973585 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL11226017 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL9488340 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL21340183 | 0.76 | ESR1 (0.50) | ALDH1A1HPGDHSD17B10TDP1CA2 | |
| SCHEMBL10926885 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189191-A | Free-radical generating aromatic diols, polycarbonates containing thermal labile groups and their conversion to polycarbonate block copolymers | GENERAL ELECTRIC COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| US-5140078-A | Free-radical generating aromatic diols, polycarbonates containing thermal labile groups and their conversion to polycarbonate block copolymers | GENERAL ELECTRIC COMPANY (US) | 1992-08-18 | — | — | US | disclosed |
| US-5079310-A | Free-radical generating aromatic diols, polycarbonates containing thermal labile groups and their conversion to polycarbonate block copolymers | GENERAL ELECTRIC COMPANY (US) | 1992-01-07 | — | — | US | disclosed |