Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475876 | 0.88 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476674 | 0.88 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9474779 | 0.87 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475938 | 0.85 | ABCC9 (0.35) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475850 | 0.84 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8027470 | 0.84 | — | — | |
| SCHEMBL9475265 | 0.81 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475563 | 0.80 | CHRM1 (0.31) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476803 | 0.79 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476029 | 0.78 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |