SCHEMBL9475884

SCHEMBL9475884

O=c1oc(-c2ccccc2-c2nc3ccccc3c(=O)o2)nc2ccccc12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C1R P00736 7/20 0.78
KMT2A Q03164 4/20 0.78
F2 P00734 4/20 0.78
PLG P00747 1/20 0.78
KLK1 P06870 1/20 0.78
PRSS1 P07477 1/20 0.78
C1S P09871 1/20 0.78
ATM Q13315 1/20 0.78
L3MBTL1 Q9Y468 1/20 0.78
ELANE P08246 5/20 0.73
MEN1 O00255 3/20 0.69
MAPT P10636 1/20 0.69
ALDH1A1 P00352 3/20 0.63
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
KDM4E B2RXH2 2/20 0.63
HPGD P15428 2/20 0.63
NPSR1 Q6W5P4 1/20 0.63
RXFP1 Q9HBX9 1/20 0.63
SMN1; SMN2 Q16637 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29791056 1.00 C1R (0.78) C1RKMT2AF2PLGKLK1
SCHEMBL18963257 0.98 C1R (0.76) C1RKMT2AF2PLGKLK1
SCHEMBL9475739 0.94 C1R (0.76) C1RKMT2AF2PLGKLK1
SCHEMBL11815601 0.93 ELANE (0.75) C1RKMT2AF2PLGKLK1
SCHEMBL2537274 0.92 ELANE (0.73) C1RKMT2AF2PLGKLK1
SCHEMBL30914649 0.92 ELANE (0.73) C1RKMT2AF2PLGKLK1
SCHEMBL272287 0.90 ELANE (0.81) C1RKMT2AF2PLGKLK1
SCHEMBL2816912 0.90 C1R (0.69) C1RKMT2AF2PLGKLK1
SCHEMBL913682 0.88 C1R (0.68) C1RKMT2AF2PLGKLK1
SCHEMBL5299192 0.88 C1R (1.00) C1RKMT2AF2PLGKLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3075559-B1 TRANSPARENT LASER MARKING SHEET, LAMINATE, AND METHOD FOR LASER MARKING MITSUBISHI CHEM CORP (JP) 2019-01-30 EP disclosed
EP-3075559-A1 TRANSPARENT LASER MARKING SHEET, LAMINATE, AND METHOD FOR LASER MARKING Mitsubishi Plastics, Inc. (JP) 2016-10-05 EP disclosed
EP-3056488-A1 BISBENZOXAZINONE COMPOUND Teijin Chemicals, Ltd. (JP) 2016-08-17 EP disclosed
EP-2505585-B1 BIS-BENZOXAZINONE COMPOUND TEIJIN CHEMICALS LTD (JP) 2016-08-03 EP disclosed
EP-2670904-A1 STABILIZED ULTRA HIGH MOLECULAR WEIGHT POLYOLEFIN FIBER DSM IP Assets B.V. (NL) 2013-12-11 EP disclosed
US-20120252941-A1 BISBENZOXAZINONE COMPOUND TEIJIN CHEMICALS, LTD. (JP) 2012-10-04 US disclosed
EP-2505585-A1 BIS-BENZOXAZINONE COMPOUND Teijin Chemicals, Ltd. (JP) 2012-10-03 EP disclosed
WO-2012104302-A1 STABILIZED ULTRA HIGH MOLECULAR WEIGHT POLYOLEFIN FIBER DSM IP ASSETS B.V. (NL) 2012-08-09 WO disclosed
US-5264539-A Heat resistant films, fibers or moldings with radiation resistance HOECHST CELANESE CORP. (US) 1993-11-23 US disclosed
WO-1993021167-A1 THERMALLY STABLE OLIGOMERIC ULTRAVIOLET STABILIZERS HOECHST CELANESE CORPORATION (US) 1993-10-28 WO disclosed
US-5234681-A A phenylene-, naphthylene- or biphenylenebis(3,1-benzoxazin-4-one; sunscreen agents; colorless, odorless and nonirritating; durability TEIJIN LIMITED (JP) 1993-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252941-A1 BISBENZOXAZINONE COMPOUND RPS4Y1, RPS4X, H1-4 C1R 298/4885KMT2A 947/4885F2 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.