SCHEMBL2537274

SCHEMBL2537274

O=c1oc(-c2ccc(-c3nc4ccccc4c(=O)o3)c3ccccc23)nc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.73
C1R P00736 7/20 0.73
F2 P00734 4/20 0.73
KMT2A Q03164 4/20 0.73
PLG P00747 1/20 0.73
KLK1 P06870 1/20 0.73
PRSS1 P07477 1/20 0.73
C1S P09871 1/20 0.73
ATM Q13315 1/20 0.73
L3MBTL1 Q9Y468 1/20 0.73
MEN1 O00255 3/20 0.65
MAPT P10636 2/20 0.65
ALDH1A1 P00352 4/20 0.63
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
KDM4E B2RXH2 3/20 0.63
HPGD P15428 2/20 0.63
NPSR1 Q6W5P4 1/20 0.63
RXFP1 Q9HBX9 1/20 0.63
SMN1; SMN2 Q16637 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30914649 1.00 ELANE (0.73) ELANEC1RF2KMT2APLG
SCHEMBL9475739 0.94 C1R (0.76) ELANEC1RF2KMT2APLG
SCHEMBL29791056 0.92 C1R (0.78) ELANEC1RF2KMT2APLG
SCHEMBL9475884 0.92 C1R (0.78) ELANEC1RF2KMT2APLG
SCHEMBL18963257 0.91 C1R (0.76) ELANEC1RF2KMT2APLG
SCHEMBL272287 0.90 ELANE (0.81) ELANEC1RF2KMT2APLG
SCHEMBL2816912 0.90 C1R (0.69) ELANEC1RF2KMT2APLG
SCHEMBL11815601 0.86 ELANE (0.75) ELANEC1RF2KMT2APLG
SCHEMBL272702 0.85 ELANE (1.00) ELANEC1RF2KMT2APLG
SCHEMBL29382161 0.85 ELANE (1.00) ELANEC1RF2KMT2APLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040219390-A1 Benzoxazinone and quinazolinone derivatives HONEYWELL INTERNATIONAL, INC. (US) 2004-11-04 US claimed
WO-2004066315-A2 BENZOXAZINONE AND QUINAZOLINONE DERIVATIVES HONEYWELL INTERNATIONAL INC. (US) 2004-08-05 WO claimed
WO-2004059604-A2 METHOD AND SYSTEM FOR FABRICATING AN OLED HONEYWELL INTERNATIONAL, INC. (US) 2004-07-15 WO claimed
US-20040132228-A1 Method and system for fabricating an OLED HONEYWELL INTERNATIONAL INC. (US) 2004-07-08 US claimed
US-12242095-B2 Optical film, polarizing plate, surface plate for image display device, and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2025-03-04 US disclosed
US-20210405272-A1 OPTICAL FILM, POLARIZING PLATE, SURFACE PLATE FOR IMAGE DISPLAY DEVICE, AND IMAGE DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2021-12-30 US disclosed
CN-113272689-A Optical film, polarizing plate, surface plate for image display device, and image display device 大日本印刷株式会社 2021-08-17 CN disclosed
CN-108780169-B Light source unit, laminated member, and display and lighting device using the same 东丽株式会社 2020-06-05 CN disclosed
EP-2267067-B1 Ultraviolet absorber composition and resin composition stabilized with the absorber composition FUJIFILM CORP (JP) 2015-08-12 EP disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20040219390-A1 Benzoxazinone and quinazolinone derivatives HONEYWELL INTERNATIONAL, INC. (US) 2004-11-04 US disclosed
WO-2004066315-A2 BENZOXAZINONE AND QUINAZOLINONE DERIVATIVES HONEYWELL INTERNATIONAL INC. (US) 2004-08-05 WO disclosed
WO-2004059604-A2 METHOD AND SYSTEM FOR FABRICATING AN OLED HONEYWELL INTERNATIONAL, INC. (US) 2004-07-15 WO disclosed
US-20040132228-A1 Method and system for fabricating an OLED HONEYWELL INTERNATIONAL INC. (US) 2004-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040219390-A1 Benzoxazinone and quinazolinone derivatives XDH, AOX1, CYP4X1 ELANE 3064/4885C1R 4350/4885F2 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.