SCHEMBL9476176

SCHEMBL9476176

CC(c1ccc(C#Cc2cccs2)cc1)N(O)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 17/20 0.55
FFAR1 O14842 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9195264 0.88 FFAR1 (0.47) ALOX5FFAR1
SCHEMBL9474461 0.82 ALOX5 (0.73) ALOX5FFAR1
SCHEMBL9475217 0.79 ALOX5 (0.65) ALOX5
SCHEMBL9475741 0.79 ALOX5 (0.50) ALOX5
SCHEMBL9475942 0.77 ALOX5 (0.66) ALOX5
SCHEMBL9197580 0.77 FFAR1 (0.43) ALOX5FFAR1
SCHEMBL9476202 0.74 ALOX5 (0.57) ALOX5
SCHEMBL9477211 0.74 FFAR1 (0.58) ALOX5FFAR1
SCHEMBL9192430 0.72 FFAR1 (0.46) FFAR1
SCHEMBL9474803 0.71 ALOX5 (1.00) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202349-A Lipoxygenase inhibitors, antiasthatics GRUENENTHAL GMBH (DE) 1993-04-13 US disclosed