Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476176 | 0.88 | ALOX5 (0.55) | FFAR1ALOX5 | |
| SCHEMBL9197580 | 0.83 | FFAR1 (0.43) | FFAR1ALOX5ERN1 | |
| SCHEMBL9195413 | 0.82 | FFAR1 (0.54) | FFAR1ALOX5 | |
| SCHEMBL9195927 | 0.80 | ACACB (0.49) | FFAR1ALOX5 | |
| SCHEMBL9192424 | 0.78 | ALOX5 (0.48) | FFAR1ALOX5 | |
| SCHEMBL9195590 | 0.78 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL9197164 | 0.77 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL9190852 | 0.75 | FFAR1 (0.58) | FFAR1ALOX5ERN1 | |
| SCHEMBL9190073 | 0.74 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL9192430 | 0.73 | FFAR1 (0.46) | FFAR1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468281-B1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | GRUENENTHAL GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |
| EP-0468281-A1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | Grünenthal GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |