Caffeic Acid

Caffeic Acid

SCHEMBL9477189

O=C(O)C=Cc1ccc(O)c(O)c1.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.96
HSD17B10 Q99714 3/20 0.96
CA12 O43570 3/20 0.96
CA1 P00915 3/20 0.96
CA2 P00918 3/20 0.96
CA3 P07451 3/20 0.96
CA4 P22748 3/20 0.96
CA6 P23280 3/20 0.96
CA5A P35218 3/20 0.96
CA7 P43166 3/20 0.96
CA9 Q16790 3/20 0.96
CA14 Q9ULX7 3/20 0.96
CA5B Q9Y2D0 3/20 0.96
MAPT P10636 2/20 0.96
TTR P02766 2/20 0.96
APP P05067 2/20 0.96
AKR1B10 O60218 2/20 0.96
AKR1B1 P15121 2/20 0.96
DPP4 P27487 2/20 0.96
MMP1 P03956 2/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caffeic Acid SCHEMBL9477179 1.00 KDM4E (0.96) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL7064846 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL1262229 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL30050844 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL29353048 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL23358 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL3682144 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL29447135 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL21114743 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2
Caffeic Acid SCHEMBL30501140 0.98 KDM4E (1.00) KDM4EHSD17B10CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5117145-A None JP disclosed
CN-106236840-A Improve the preparation method of the pharmaceutical composition of Radix Illicii Lanceolati drug injection preparation stability 成都佳迪璐莎生物科技有限公司 2016-12-21 CN disclosed
CN-1320424-A Application of sodium 3,4-dihydroxycinnamate in preparing antineoplastics INST OF MEDICAL BIOLOGY CHINES (CN) 2001-11-07 CN disclosed
JP-H05117145-A COLLAGENASE ACTIVITY INHIBITOR KANEBO LTD 1993-05-14 JP disclosed