Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891644 | 0.94 | NFE2L2 (0.65) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL17732236 | 0.94 | NFE2L2 (0.65) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL13267811 | 0.87 | RELA (0.71) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL1900344 | 0.87 | RELA (0.71) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL25233853 | 0.87 | RELA (0.71) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL8350728 | 0.81 | KDM4E (0.87) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL4881152 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL14950253 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL631998 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL13790336 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377469-B1 | A LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5183587-A | LIQUID CRYSTALLINE COMPOUND | CHISSO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0377469-A1 | A liquid crystalline compound | CHISSO CORPORATION (JP) | 1990-07-11 | — | — | EP | disclosed |