Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477319 | 1.00 | ALDH1A1 (0.33) | ALDH1A1GLATDP1 | |
| SCHEMBL9911578 | 0.77 | — | — | |
| SCHEMBL279294 | 0.77 | — | — | |
| SCHEMBL29130650 | 0.75 | — | — | |
| SCHEMBL14985381 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL14239242 | 0.69 | — | — | |
| SCHEMBL28437322 | 0.67 | ALDH1A1 (0.41) | ALDH1A1GLATDP1 | |
| SCHEMBL15286796 | 0.65 | TSHR (0.64) | ALDH1A1GLATDP1 | |
| SCHEMBL819289 | 0.65 | — | — | |
| SCHEMBL5708684 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013062-A1 | HALOGENATED TETRAENYL PROSTAGLANDIN DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5177251-A | Cytoprotective, antisecretory, side effect reduction | G. D. SEARLE & CO. (US) | 1993-01-05 | — | — | US | disclosed |