Metolcarb

Metolcarb

SCHEMBL9477374

CNC(=O)Oc1cccc(C)c1.O=[PH](O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
ALDH1A1 P00352 6/20 0.52
MAPK1 P28482 2/20 0.52
FAAH O00519 1/20 0.52
CYP3A4 P08684 1/20 0.52
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
NPC1 O15118 2/20 0.46
HPGD P15428 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
THRB P10828 1/20 0.46
KMT2A Q03164 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALOX5 P09917 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolcarb SCHEMBL118244 0.93 LMNA (0.65) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL29413999 0.93 LMNA (0.65) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL8051854 0.92 LMNA (0.53) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL8024716 0.92 LMNA (0.62) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL11681132 0.92 LMNA (0.62) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL11000289 0.92 LMNA (0.62) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL7079404 0.92 LMNA (0.62) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL28786421 0.92 LMNA (0.62) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL1879809 0.90 LMNA (0.61) LMNAALDH1A1MAPK1FAAHCYP3A4
Metolcarb SCHEMBL9780604 0.89 LMNA (0.49) LMNAALDH1A1MAPK1FAAHCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190345639-A1 POLY(PHENYLENE ETHER) FIBER, METHOD OF FORMING, AND ARTICLES THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2019-11-14 US disclosed
EP-3084053-A1 POLY(PHENYLENE ETHER) FIBER, METHOD OF FORMING, AND ARTICLES THEREFROM SABIC Global Technologies B.V. (NL) 2016-10-26 EP disclosed
US-20150166789-A1 POLY(PHENYLENE ETHER) FIBER, METHOD OF FORMING, AND ARTICLES THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2015-06-18 US disclosed
US-5191000-A FLAMEPROOFED, NON-DRIPPING POLYALKYLENE TEREPHTHALATE MOLDING COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1993-03-02 US disclosed