Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087129 | 0.81 | ALDH1A1 (0.42) | HSD17B10ALDH1A1LMNACYP2C19 | |
| SCHEMBL19112483 | 0.81 | TET2 (0.48) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL928308 | 0.78 | RIPK1 (0.33) | HSD17B10LMNACYP2C19 | |
| SCHEMBL12388730 | 0.78 | TET2 (0.54) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL931019 | 0.74 | POLB (0.33) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13448448 | 0.72 | TET2 (0.48) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL2871996 | 0.72 | CNR1 (0.44) | HSD17B10KDM4ECA14ALDH1A1MEN1 | |
| SCHEMBL13444980 | 0.71 | RECQL (0.61) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL14440671 | 0.71 | TET2 (0.52) | TET2RECQLTSHRHSD17B10GAA | |
| SCHEMBL10266048 | 0.71 | TET2 (0.47) | TET2RECQLTSHRHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266713-A | Aryl alkenoic acid derivatives as leukotriene antagonists | MILES INC. (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0410241-B1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1993-10-20 | — | — | EP | disclosed |
| EP-0410241-A1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |