SCHEMBL947874

SCHEMBL947874

CCOCCOS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.44
CA2 P00918 5/20 0.44
CA12 O43570 2/20 0.37
CA7 P43166 2/20 0.37
CA13 Q8N1Q1 2/20 0.37
CA9 Q16790 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27865960 0.81 CA1 (0.44) CA1CA2CA12CA7CA13
SCHEMBL21667232 0.77 CA1 (0.50) CA1CA2CA12CA7CA13
SCHEMBL4870631 0.77 RECQL (0.50) CA1CA2CA12CA7CA13
SCHEMBL15152520 0.70 CA2 (0.42) CA1CA2CA12CA7CA13
SCHEMBL6573700 0.69 ALDH1A1 (0.42) CA1CA2CA12CA7CA9
SCHEMBL15152532 0.69 CA1 (0.41) CA1CA2CA12CA7CA13
SCHEMBL15152530 0.69 CA1 (0.41) CA1CA2CA12CA7CA13
SCHEMBL15475636 0.69 RECQL (0.54) CA1CA2ALDH1A1TSHRGAA
Lithium Ion SCHEMBL17456396 0.69 RECQL (0.48) CA1CA2ALDH1A1TSHRGAA
SCHEMBL15173534 0.68 CA1 (0.41) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7872122-B2 Process for making Biolimus A9 CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO., LTD. (TW) 2011-01-18 US claimed
US-20090292118-A1 Process for making Biolimus A9 CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO., LTD. (TW) 2009-11-26 US claimed
US-7872122-B2 Process for making Biolimus A9 CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO., LTD. (TW) 2011-01-18 US disclosed
US-20090292118-A1 Process for making Biolimus A9 CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO., LTD. (TW) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090292118-A1 Process for making Biolimus A9 RICTOR, MRPL9, RPS9 CA1 4808/4885CA2 4441/4885CA12 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.