SCHEMBL9478751

SCHEMBL9478751

CCCCC1CCC(CCc2ccc(C=CF)cc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.39
MAOA P21397 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
CYP1A2 P05177 1/20 0.37
TNNC1 P63316 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
SPHK1 Q9NYA1 3/20 0.34
KMT2A Q03164 1/20 0.34
SPHK2 Q9NRA0 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9478757 1.00 MAOB (0.39) MAOBMAOAHRH3CYP1A2TNNC1
SCHEMBL9476700 0.96 MAOA (0.38) MAOBMAOAHRH3TNNC1SPHK1
SCHEMBL9476691 0.96 MAOA (0.38) MAOBMAOAHRH3TNNC1SPHK1
SCHEMBL9480091 0.94 TNNC1 (0.40) MAOBMAOATNNC1SPHK1SPHK2
SCHEMBL9480098 0.94 TNNC1 (0.40) MAOBMAOATNNC1SPHK1SPHK2
SCHEMBL9477243 0.91 MAOB (0.40) MAOBMAOAHRH3TNNC1GPR84
SCHEMBL9477234 0.91 MAOB (0.40) MAOBMAOAHRH3TNNC1GPR84
SCHEMBL9476465 0.88 MAOB (0.38) MAOBMAOAGPR84
SCHEMBL9476473 0.88 MAOB (0.38) MAOBMAOAGPR84
SCHEMBL9477176 0.82 CYP2C9 (0.43) MAOBMAOACYP1A2SPHK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377469-B1 A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5183587-A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-02-02 US disclosed
EP-0377469-A1 A liquid crystalline compound CHISSO CORPORATION (JP) 1990-07-11 EP disclosed