Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479119 | 0.91 | POLB (0.52) | RAB9ACYP3A4POLBEPHX2NR1H4 | |
| SCHEMBL9480828 | 0.83 | CYSLTR1 (0.52) | TDP1NPSR1CYP2C9POLBEPHX2 | |
| SCHEMBL9479292 | 0.79 | EPHX2 (0.56) | KDM4ELMNATDP1ALDH1A1NPSR1 | |
| SCHEMBL9480375 | 0.78 | KCNQ3 (0.53) | KDM4ELMNARAB9AALDH1A1NPSR1 | |
| SCHEMBL9479510 | 0.76 | ALDH1A1 (0.51) | KDM4ELMNARAB9ATDP1ALDH1A1 | |
| SCHEMBL9478986 | 0.75 | EPHX2 (0.66) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL10367852 | 0.73 | EPHX2 (0.66) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9187597 | 0.73 | EPHX2 (0.48) | KDM4ELMNAALDH1A1NPSR1CYP3A4 | |
| SCHEMBL9479619 | 0.70 | CYSLTR2 (0.46) | EPHX2NR1H4CYSLTR2CYSLTR1CNR1 | |
| SCHEMBL8951110 | 0.68 | CHRNA7 (0.52) | KDM4ELMNARAB9ATDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234942-A | Treating allergic pulmonary disorders, asthma | ICI AMERICAS INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-4997844-A | Compounds for the treatment of allergic or inflammatory diseases or shock conditions | ICI AMERICAS INC. (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0179619-B1 | HETEROCYCLIC AMIDES | ICI AMERICAS INC. (US) | 1990-09-05 | — | — | EP | disclosed |