Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18837639 | 1.00 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837605 | 1.00 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL237268 | 1.00 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837600 | 1.00 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837623 | 0.95 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837621 | 0.95 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837626 | 0.95 | GAA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837678 | 0.95 | GAA (0.49) | GAAKMT2AMEN1ALOX5PKM | |
| SCHEMBL11674242 | 0.92 | DGKA (0.47) | GAAKMT2ADGKACNR2PLA2G4B | |
| SCHEMBL18837642 | 0.92 | GAA (0.48) | GAAKMT2ACNR2PLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053449-B2 | Thioether-containing phenolic compounds | THE LUBRIZOL CORPORATION (US) | 2021-07-06 | — | — | US | claimed |
| EP-3374478-B1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | LUBRIZOL CORP (US) | 2021-01-06 | — | — | EP | claimed |
| US-20200239805-A1 | THIOETHER-CONTAINING PHENOLIC COMPOUNDS | THE LUBRIZOL CORPORATION | 2020-07-30 | — | — | US | claimed |
| EP-3374478-A1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | The Lubrizol Corporation (US) | 2018-09-19 | — | — | EP | claimed |
| WO-2017083243-A1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | THE LUBRIZOL CORPORATION (US) | 2017-05-18 | — | — | WO | claimed |
| US-11053449-B2 | Thioether-containing phenolic compounds | THE LUBRIZOL CORPORATION (US) | 2021-07-06 | — | — | US | disclosed |
| EP-3374478-B1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | LUBRIZOL CORP (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20200239805-A1 | THIOETHER-CONTAINING PHENOLIC COMPOUNDS | THE LUBRIZOL CORPORATION | 2020-07-30 | — | — | US | disclosed |
| EP-3374478-A1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | The Lubrizol Corporation (US) | 2018-09-19 | — | — | EP | disclosed |
| CN-108473899-A | Lubricating composition containing thioether-substituted phenol compound | 路博润公司 | 2018-08-31 | — | — | CN | disclosed |
| WO-2017083243-A1 | LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND | THE LUBRIZOL CORPORATION (US) | 2017-05-18 | — | — | WO | disclosed |
| US-5268113-A | Blend of an oil and a steric hindered amine | CIBA-GEIGY CORPORATION (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0406826-B1 | LUBRICANT COMPOSITION | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | disclosed |
| EP-0406826-A1 | Lubricant composition | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053449-B2 | Thioether-containing phenolic compounds | TST, TH, COMT | GAA 2743/4885KMT2A 1728/4885DGKA 2319/4885 |
| US-20200239805-A1 | THIOETHER-CONTAINING PHENOLIC COMPOUNDS | TST, TH, COMT | GAA 2743/4885KMT2A 1728/4885DGKA 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.