Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNN2 | Q9H2S1 | 3/20 | 0.42 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580531 | 0.87 | POLB (0.37) | MAOAMAOBSLC6A4ABCB1HDAC1 | |
| SCHEMBL9480009 | 0.83 | ABCB1 (0.55) | MAOAMAOBSLC6A4ABCB1MAPT | |
| Bromide SCHEMBL27344472 | 0.82 | ABCB1 (0.54) | MAOAMAOBSLC6A4ABCB1MAPT | |
| SCHEMBL9491572 | 0.80 | MAOA (0.42) | MAOAMAOBSLC6A4ABCB1HDAC1 | |
| SCHEMBL12718802 | 0.76 | HRH3 (0.51) | HDAC1HDAC6 | |
| SCHEMBL22049279 | 0.76 | MEN1 (0.59) | MAOAMAOBSLC6A4ABCB1MAPT | |
| SCHEMBL12656336 | 0.74 | HTR2A (0.49) | HDAC1HDAC6CYP3A4 | |
| SCHEMBL107921 | 0.74 | NOTUM (0.40) | MAOA | |
| SCHEMBL29803467 | 0.74 | NOTUM (0.40) | MAOA | |
| SCHEMBL27204446 | 0.74 | CHRNB4 (0.45) | MAOAMAOBSLC6A4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5178637-A | Hair dyes | L'OREAL (FR) | 1993-01-12 | — | — | US | disclosed |