SCHEMBL9479727

SCHEMBL9479727

COc1ccc(N(C)c2ccc(N(C)c3ccccc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.56
EGFR P00533 2/20 0.54
PDGFRB P09619 2/20 0.54
KDR P35968 2/20 0.54
LTA4H P09960 2/20 0.54
CES1 P23141 1/20 0.51
CASP1 P29466 1/20 0.51
CASP14 P31944 1/20 0.51
CASP3 P42574 1/20 0.51
CASP2 P42575 1/20 0.51
CASP4 P49662 1/20 0.51
CASP5 P51878 1/20 0.51
CASP7 P55210 1/20 0.51
CASP9 P55211 1/20 0.51
CASP6 P55212 1/20 0.51
CASP8 Q14790 1/20 0.51
CASP12 Q6UXS9 1/20 0.51
CASP10 Q92851 1/20 0.51
MERTK Q12866 1/20 0.50
CA12 O43570 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5277509 1.00 CA4 (0.56) CA4EGFRPDGFRBKDRLTA4H
SCHEMBL13241204 0.94 EGFR (0.50) CA4EGFRPDGFRBKDRLTA4H
SCHEMBL12047752 0.94 EGFR (0.50) CA4EGFRPDGFRBKDRLTA4H
SCHEMBL114319 0.91 CA1 (0.61) EGFRPDGFRBKDRCES1CASP1
SCHEMBL13241207 0.90 EGFR (0.50) CA4EGFRPDGFRBKDRLTA4H
SCHEMBL9480806 0.89 RAB9A (0.61) EGFRPDGFRBKDRMERTKKDM4E
SCHEMBL12048277 0.89 EGFR (0.47) CA4EGFRPDGFRBKDRLTA4H
Hydrochloric Acid SCHEMBL29089898 0.88 CA1 (0.58) EGFRPDGFRBKDRCES1CASP1
SCHEMBL12047852 0.87 EGFR (0.46) CA4EGFRPDGFRBKDRLTA4H
SCHEMBL12048227 0.87 ACHE (0.52) CA4EGFRPDGFRBKDRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210065-A A mixture of an aromatic amine, an oxidizer and an acid MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-05-11 US disclosed
EP-0479578-A1 Color-forming recording material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 EP disclosed