Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344500 | 0.91 | THRB (0.59) | THRBTSHRALDH1A1EPHX2HSD17B10 | |
| SCHEMBL3459308 | 0.90 | THRB (0.52) | THRBTSHRALDH1A1HSD17B10 | |
| SCHEMBL27811842 | 0.89 | THRB (0.61) | THRBTSHRALDH1A1EPHX2HSD17B10 | |
| SCHEMBL28134906 | 0.89 | THRB (0.61) | THRBTSHRALDH1A1EPHX2HSD17B10 | |
| SCHEMBL111960 | 0.86 | THRB (0.68) | THRBTSHRALDH1A1EPHX2HSD17B10 | |
| Methacrylic Acid SCHEMBL28915677 | 0.84 | THRB (0.57) | THRBTSHRALDH1A1EPHX2 | |
| SCHEMBL824127 | 0.84 | THRB (0.66) | THRBTSHRALDH1A1EPHX2HSD17B10 | |
| SCHEMBL5310908 | 0.83 | THRB (0.46) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL28167972 | 0.82 | THRB (0.48) | THRBTSHRALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL27688472 | 0.82 | THRB (0.63) | THRBTSHRALDH1A1EPHX2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5199098-A | Polyurethane-acrylate | CORNING INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |
| EP-0374050-A1 | Improved desiccant for el lamps | LOCTITE LUMINESCENT SYSTEMS, INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4923915-A | Thermally stabilized resin coatings for optical fibers | CORNING INCORPORATED (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0343760-A2 | Thermally stabilized resin coatings for optical fibers | Corning Glass Works (US) | 1989-11-29 | — | — | EP | disclosed |