Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246218 | 0.93 | THRB (0.46) | THRBTSHRCYP3A4DGKAALDH1A1 | |
| SCHEMBL27503739 | 0.84 | TSHR (0.42) | THRBTSHRCYP3A4ALDH1A1HPGD | |
| SCHEMBL9480340 | 0.83 | THRB (0.66) | THRBTSHRDGKAALDH1A1TP53 | |
| SCHEMBL9056869 | 0.83 | THRB (0.43) | THRBTSHRCYP3A4DGKAALDH1A1 | |
| SCHEMBL11033121 | 0.83 | MEN1 (0.47) | THRBTSHRCYP3A4DGKAALDH1A1 | |
| SCHEMBL25403843 | 0.83 | MEN1 (0.47) | THRBTSHRCYP3A4DGKAALDH1A1 | |
| SCHEMBL9056866 | 0.83 | THRB (0.43) | THRBTSHRCYP3A4DGKAALDH1A1 | |
| SCHEMBL170886 | 0.83 | TSHR (0.52) | THRBTSHRDGKAALDH1A1HPGD | |
| SCHEMBL28365041 | 0.82 | TSHR (0.52) | THRBTSHRCYP3A4DGKAALDH1A1 | |
| SCHEMBL11517487 | 0.82 | TSHR (0.52) | THRBTSHRCYP3A4DGKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007037497-A1 | OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |