Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643921 | 0.92 | MEN1 (0.40) | LMNACHRM2MGLLTDP1ALDH1A1 | |
| SCHEMBL14352937 | 0.91 | LMNA (0.44) | LMNACHRM2MGLLTDP1ALDH1A1 | |
| Methane SCHEMBL20484194 | 0.90 | MEN1 (0.39) | LMNACHRM2TDP1ALDH1A1POLB | |
| SCHEMBL36896 | 0.88 | LMNA (0.54) | LMNACHRM2TDP1ALDH1A1POLB | |
| SCHEMBL14656023 | 0.86 | ALDH1A1 (0.38) | LMNACHRM2MGLLALDH1A1POLB | |
| SCHEMBL132721 | 0.86 | MEN1 (0.43) | LMNATDP1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL9638549 | 0.85 | ESR2 (0.43) | LMNACHRM2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21401693 | 0.84 | MEN1 (0.39) | LMNACHRM2MEN1KMT2A | |
| SCHEMBL21401694 | 0.84 | MEN1 (0.39) | LMNACHRM2MEN1KMT2A | |
| SCHEMBL8763546 | 0.84 | CYP3A4 (0.42) | LMNATDP1ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206411-A | Cured arylcyclobutene carboxylate ester compositions | SHELL OIL COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| US-5068396-A | Arylcyclobutene carboxylate esters | SHELL OIL COMPANY (US) | 1991-11-26 | — | — | US | disclosed |