Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12764890 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL10140744 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL30154481 | 0.78 | GABRP (0.61) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL256024 | 0.78 | GABRP (0.61) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL6788044 | 0.77 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL167654 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL29457418 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL10140749 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL1976605 | 0.76 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL29515142 | 0.76 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |