Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | TDO2 | P48775 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | GABRP | O00591 | 1/20 | 1.00 |
| ▸ | GABRD | O14764 | 1/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | GABRB1 | P18505 | 1/20 | 1.00 |
| ▸ | GABRG2 | P18507 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Harman SCHEMBL141723 | 1.00 | MAOA (1.00) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL9754741 | 1.00 | MAOA (1.00) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL29630272 | 1.00 | MAOA (1.00) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL3764237 | 0.98 | MAOA (0.96) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL9717439 | 0.98 | MAOA (0.96) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL6081891 | 0.96 | MAOA (0.93) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL10384803 | 0.87 | MAOA (0.75) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL9150535 | 0.81 | MAOA (0.66) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL9482944 | 0.81 | KDM4E (0.71) | MAOAKDM4EALDH1A1TDO2MEN1 | |
| Harman SCHEMBL9754744 | 0.81 | KDM4E (0.71) | MAOAKDM4EALDH1A1TDO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256533-A | Preincubating sample with an alpha-2-inhibitor; comparing fluorescence in test to control tissues | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 1993-10-26 | — | — | US | disclosed |