Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | MEN1 | O00255 | 9/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | HTR2C | P28335 | 5/20 | 0.71 |
| ▸ | HTR7 | P34969 | 4/20 | 0.71 |
| ▸ | HTR6 | P50406 | 4/20 | 0.71 |
| ▸ | HTR2A | P28223 | 3/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | HTR5A | P47898 | 2/20 | 0.71 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.66 |
| ▸ | BLM | P54132 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Harman SCHEMBL9482944 | 1.00 | KDM4E (0.71) | KDM4EMEN1KMT2AMAPTHTR2C | |
| SCHEMBL9480941 | 0.84 | MEN1 (1.00) | KDM4EMEN1KMT2AMAPTHTR2C | |
| SCHEMBL141724 | 0.84 | MEN1 (1.00) | KDM4EMEN1KMT2AMAPTHTR2C | |
| SCHEMBL31002948 | 0.83 | MEN1 (0.97) | KDM4EMEN1KMT2AMAPTHTR2C | |
| Hydrochloric Acid SCHEMBL3764244 | 0.83 | MEN1 (0.97) | KDM4EMEN1KMT2AMAPTHTR2C | |
| SCHEMBL9717445 | 0.83 | MEN1 (0.97) | KDM4EMEN1KMT2AMAPTHTR2C | |
| Hydrochloric Acid SCHEMBL6081896 | 0.81 | MEN1 (0.94) | KDM4EMEN1KMT2AMAPTHTR2C | |
| Harman SCHEMBL9480937 | 0.81 | MAOA (1.00) | KDM4EMEN1KMT2AMAPTHTR2C | |
| Harman SCHEMBL141723 | 0.81 | MAOA (1.00) | KDM4EMEN1KMT2AMAPTHTR2C | |
| Harman SCHEMBL29630272 | 0.81 | MAOA (1.00) | KDM4EMEN1KMT2AMAPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014184-A1 | BETA CARBOLINES AS VITAL STAINS FOR NEUROTRANSMITTER SYSTEMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-09-19 | — | — | WO | disclosed |