Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923373 | 0.86 | PRCP (0.40) | PRCPSLC22A1CYP2D6HTR2CHTR2A | |
| SCHEMBL38665128 | 0.85 | CYP2D6 (0.39) | PRCPSLC22A1CYP2D6HTR2CHTR2A | |
| SCHEMBL29532113 | 0.85 | CYP2D6 (0.39) | PRCPSLC22A1CYP2D6HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL814140 | 0.84 | ALDH1A1 (0.38) | PRCPSLC22A1CYP2D6HTR2CHTR2A | |
| SCHEMBL6429588 | 0.84 | PRCP (0.59) | PRCPSLC22A1OPRM1OPRK1SMN1; SMN2 | |
| SCHEMBL11805092 | 0.83 | PRCP (0.46) | PRCPSLC22A1CYP2D6MEN1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28831335 | 0.82 | PRCP (0.57) | PRCPSLC22A1OPRM1OPRK1SMN1; SMN2 | |
| SCHEMBL27620851 | 0.82 | PRCP (0.41) | PRCPSLC22A1PNMTHTR2A | |
| SCHEMBL27985631 | 0.79 | PRCP (0.60) | PRCPSLC22A1OPRM1OPRK1SMN1; SMN2 | |
| SCHEMBL1248364 | 0.78 | BCHE (0.41) | CYP2D6MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268372-A | Where nitrogen in position 2 and 5 are connected by a methylene bridge | STERLING WINTHROP INC. (US) | 1993-12-07 | — | — | US | disclosed |
| US-5206231-A | 2,5-benzodiazocine antiarrhythmic agents | STERLING DRUG INC. (US) | 1993-04-27 | — | — | US | disclosed |