Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 10/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94360 | 0.81 | ALDH1A1 (0.39) | CNR2ARCRHR1MME | |
| SCHEMBL95044 | 0.78 | AR (0.56) | CNR2ARCNR1CRHR1MME | |
| SCHEMBL94074 | 0.71 | AR (0.56) | CNR2ARCNR1CRHR1MME | |
| SCHEMBL1587823 | 0.68 | CNR2 (0.43) | CNR2ARCNR1CRHR1MLYCD | |
| SCHEMBL94067 | 0.66 | AR (0.50) | CNR2ARCRHR1MME | |
| SCHEMBL94819 | 0.66 | AR (0.63) | CNR2ARCRHR1MME | |
| SCHEMBL3061013 | 0.66 | CNR2 (0.58) | CNR2ARCNR1CRHR1MLYCD | |
| SCHEMBL3057299 | 0.65 | CNR2 (0.57) | CNR2ARCNR1CRHR1 | |
| SCHEMBL3050424 | 0.65 | CNR2 (0.47) | CNR2ARCNR1CRHR1 | |
| SCHEMBL13456175 | 0.65 | CNR2 (0.72) | CNR2ARCNR1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2426117-A1 | THIOPHENE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | AR, NR5A1, SHBG | CNR2 305/4885AR 1/4885CNR1 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.