Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483797 | 0.97 | FBP1 (0.39) | FBP1CES2CES1TSHRHSD17B10 | |
| SCHEMBL15452914 | 0.94 | FBP1 (0.38) | FBP1CES2CES1TSHRHSD17B10 | |
| SCHEMBL15452846 | 0.94 | FBP1 (0.38) | FBP1CES2CES1TSHRHSD17B10 | |
| Potassium Ion SCHEMBL2852074 | 0.94 | FBP1 (0.38) | FBP1CES2CES1TSHRHSD17B10 | |
| SCHEMBL187279 | 0.75 | — | — | |
| SCHEMBL5852674 | 0.74 | — | — | |
| SCHEMBL9482953 | 0.73 | DNM1 (0.39) | TSHRALDH1A1KDM4EMAPTL3MBTL1 | |
| Potassium Ion SCHEMBL15009078 | 0.72 | FBP1 (0.35) | FBP1CES2CES1TSHRHSD17B10 | |
| SCHEMBL17136143 | 0.61 | FBP1 (0.39) | FBP1CES2CES1TSHRHSD17B10 | |
| Lithium Ion SCHEMBL8563402 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969862-B2 | Organic electroluminescent element, method for manufacturing organic electroluminescent element, and coating liquid for electron injection and transport layer | DAI NIPPON PRINTING CO., LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| EP-2693506-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT ELEMENT, AND COATING LIQUID FOR ELECTRON INJECTION/TRANSPORT LAYER | Dai Nippon Printing Co., Ltd. (JP) | 2014-02-05 | — | — | EP | disclosed |
| EP-0568151-A2 | Melt transesterification process for the production of polycarbonates | ENICHEM S.p.A. (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5221761-A | Reacting a bis(arl)carbonate with a dihydric phenol in the presence of a heterocyclic borate salt polymerization catalyst | INSTITUTO GUIDO DONEGANI (IT) | 1993-06-22 | — | — | US | disclosed |