Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752950 | 0.89 | MTNR1A (0.59) | L3MBTL1TDP1MTNR1AMTNR1BHPGD | |
| SCHEMBL31429834 | 0.83 | MTNR1A (0.61) | L3MBTL1TDP1MTNR1AMTNR1BIDH1 | |
| SCHEMBL7925457 | 0.83 | MTNR1A (0.61) | L3MBTL1TDP1MTNR1AMTNR1BIDH1 | |
| SCHEMBL19036260 | 0.83 | MTNR1A (0.65) | L3MBTL1TDP1MTNR1AMTNR1BIDH1 | |
| SCHEMBL31618148 | 0.82 | KMT2A (0.50) | L3MBTL1TDP1HPGDALDH1A1MAPT | |
| SCHEMBL11776294 | 0.82 | ALDH1A1 (0.47) | L3MBTL1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL11781055 | 0.82 | ALDH1A1 (0.47) | L3MBTL1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL11778376 | 0.82 | KDM4E (0.47) | L3MBTL1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL11780237 | 0.82 | ALDH1A1 (0.47) | L3MBTL1MTNR1AMTNR1BHPGDALDH1A1 | |
| SCHEMBL29729685 | 0.81 | KMT2A (0.62) | L3MBTL1TDP1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192797-A | Antiepileptic and anticonvulsant agents | SYNTHELABO (FR) | 1993-03-09 | — | — | US | disclosed |