Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482832 | 1.00 | RARB (0.50) | RARBRARAMAPTFAAHKMT2A | |
| SCHEMBL9626761 | 0.93 | RARB (0.48) | RARBMAPTFAAHTSHR | |
| SCHEMBL9627745 | 0.93 | RARB (0.48) | RARBMAPTFAAHTSHR | |
| SCHEMBL10398275 | 0.89 | NPC1 (0.47) | MAPTFAAHTSHR | |
| SCHEMBL10397655 | 0.89 | NPC1 (0.47) | MAPTFAAHTSHR | |
| SCHEMBL9627196 | 0.89 | NPC1 (0.47) | MAPTFAAHTSHR | |
| SCHEMBL9628548 | 0.89 | NPC1 (0.47) | MAPTFAAHTSHR | |
| SCHEMBL9482808 | 0.87 | RARB (0.59) | RARBRARAMAPTKMT2AADRB2 | |
| SCHEMBL9482816 | 0.87 | RARB (0.59) | RARBRARAMAPTKMT2AADRB2 | |
| SCHEMBL10397697 | 0.87 | THRA (0.48) | RARBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258578-B1 | LIQUID CRYSTAL COMPOUNDS HAVING ETHER TAIL MOIETY | POLAROID CORPORATION (US) | 1993-01-07 | — | — | EP | disclosed |
| US-5132041-A | Liquid crystal compounds having ether tail moiety | POLAROID CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-4857227-A | Liquid crystal mixtures having widened smectic temperature range | POLAROID CORPORATION PATENT DEPARTMENT (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258578-A2 | Liquid crystal compounds having ether tail moiety | POLAROID CORPORATION (US) | 1988-03-09 | — | — | EP | disclosed |