Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483531 | 0.73 | PARP1 (0.54) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL8798234 | 0.73 | PRKCD (0.58) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL8798803 | 0.70 | PARP1 (0.54) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL3043496 | 0.70 | MAPT (0.45) | KDM4EMAPTALDH1A1TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL8798710 | 0.69 | PARP1 (0.52) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| Hydrochloric Acid SCHEMBL3052246 | 0.69 | MAPT (0.44) | KDM4EMAPTALDH1A1TSHRCYP2C19 | |
| SCHEMBL9485325 | 0.69 | PARP1 (0.51) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL8800099 | 0.68 | PARP1 (0.50) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL9483532 | 0.67 | PARP1 (0.42) | PARP1HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL8799119 | 0.67 | PARP1 (0.37) | PARP1HTR2AHTR2CHTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525584-B1 | 6-Oxo-azepinoindole derivatives, process and intermediates for their preparation and medicaments containing them | SOLVAY PHARM GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0525584-A1 | 6-Oxo-azepinoindole derivatives, process and intermediates for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |