Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.37 |
| ▸ | PRKCB | P05771 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 2/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799119 | 0.82 | PARP1 (0.37) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL1776287 | 0.76 | CRBN (0.40) | ALDH1A1MAPTRECQLCYP3A4CYP2D6 | |
| SCHEMBL8798234 | 0.75 | PRKCD (0.58) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL8798803 | 0.75 | PARP1 (0.54) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL10606538 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10606534 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Hydrochloric Acid SCHEMBL8798710 | 0.74 | PARP1 (0.52) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL9485325 | 0.73 | PARP1 (0.51) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL8800099 | 0.72 | PARP1 (0.50) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL10606204 | 0.69 | HTR7 (0.54) | ALDH1A1MEN1KMT2AHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272143-A | 6-oxoazepinoindole compounds, and pharmaceutical compositions containing them | KALI-CHEMIE PHARMA GMBH (DE) | 1993-12-21 | — | — | US | disclosed |