Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686069 | 0.82 | SIGMAR1 (0.70) | ACHESIGMAR1 | |
| SCHEMBL9483526 | 0.81 | ACHE (0.63) | ACHESIGMAR1 | |
| SCHEMBL8786318 | 0.81 | ACHE (0.56) | ACHESIGMAR1TP53MAPT | |
| SCHEMBL8620349 | 0.80 | ACHE (0.54) | ACHESIGMAR1TP53MAPTHTR1A | |
| SCHEMBL9686057 | 0.80 | ACHE (0.61) | ACHESIGMAR1 | |
| SCHEMBL7760497 | 0.78 | ACHE (0.63) | ACHESIGMAR1 | |
| SCHEMBL9484814 | 0.77 | ACHE (0.58) | ACHESIGMAR1 | |
| SCHEMBL9484562 | 0.77 | SIGMAR1 (0.69) | ACHESIGMAR1 | |
| SCHEMBL9196384 | 0.77 | ACHE (0.51) | ACHESIGMAR1TP53MAPT | |
| SCHEMBL9684507 | 0.76 | ACHE (0.60) | ACHESIGMAR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240949-A | Analgesics, blood lipid normalizing | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | claimed |
| US-5240949-A | Analgesics, blood lipid normalizing | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |
| US-5166353-A | Analgesics, anticholesterol agents, anticoagulants, antilipemic agents | ADIR ET COMPAGNIE (FR) | 1992-11-24 | — | — | US | disclosed |
| US-5162350-A | Analgesics; nontoxic; side effect reduction | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |