Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727289 | 0.85 | ATM (0.44) | ALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL5727593 | 0.81 | ERCC5 (0.40) | ALDH1A1 | |
| SCHEMBL9483959 | 0.80 | HTT (0.45) | HTTKMT2ARAB9ALMNA | |
| SCHEMBL9483366 | 0.79 | SRD5A2 (0.41) | ALDH1A1HTTKMT2A | |
| SCHEMBL9685893 | 0.77 | CNR2 (0.36) | — | |
| SCHEMBL9483334 | 0.75 | ALDH1A1 (0.48) | ALDH1A1GAAHTTKMT2ARAB9A | |
| SCHEMBL9485095 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAP2K1APPGAAHCAR3 | |
| SCHEMBL5727378 | 0.75 | MAPT (0.39) | ALDH1A1APPGAAKMT2ARAB9A | |
| SCHEMBL9484177 | 0.74 | HPGD (0.45) | ALDH1A1JAK3HTTKMT2ARAB9A | |
| SCHEMBL1242243 | 0.72 | ALDH1A1 (0.71) | ALDH1A1MAP2K1APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240949-A | Analgesics, blood lipid normalizing | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |
| US-5162350-A | Analgesics; nontoxic; side effect reduction | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |