SCHEMBL9484167

SCHEMBL9484167

C=CS(=O)(=O)c1cc(Cl)c(N)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
CA1 P00915 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 5/20 0.46
CA12 O43570 4/20 0.46
CA4 P22748 4/20 0.46
CA6 P23280 4/20 0.46
CA5A P35218 4/20 0.46
CA7 P43166 4/20 0.46
CA14 Q9ULX7 4/20 0.46
CA5B Q9Y2D0 4/20 0.46
CA3 P07451 3/20 0.46
ALDH1A1 P00352 2/20 0.41
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558883 0.89 CA1 (0.55) GAACA1CA2CA9CA12
SCHEMBL11343329 0.84 L3MBTL1 (0.40) CA1CA2CA9CA12CA4
SCHEMBL4394640 0.80 GAA (0.51) GAACA1CA2CA9CA12
SCHEMBL1708535 0.78 GAA (0.52) GAACA1CA2CA9CA12
SCHEMBL29516458 0.78 GAA (0.52) GAACA1CA2CA9CA12
SCHEMBL4386972 0.76 MAPT (0.39) CA1CA2CA9CA12CA4
SCHEMBL11284975 0.76 GAA (0.50) GAACA1CA2CA9CA12
SCHEMBL11284960 0.76 GAA (0.50) GAACA1CA2CA9CA12
Hydrochloric Acid SCHEMBL11242082 0.76 GAA (0.50) GAACA1CA2CA9CA12
SCHEMBL1035731 0.75 GAA (0.55) GAACA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5241057-A Blue shades BAYER AKTIENGESELLSHAFT (DE) 1993-08-31 US disclosed
EP-0084314-B1 REACTIVE DISAZO DYES BAYER AG (DE) 1986-07-30 EP disclosed
EP-0128316-A1 Reactive disazo dyes BAYER AG (DE) 1984-12-19 EP disclosed
EP-0084314-A2 Reactive disazo dyes BAYER AG (DE) 1983-07-27 EP disclosed