SCHEMBL4386972

SCHEMBL4386972

C=CS(=O)(=O)c1cc(OCC)c(N)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
USP2 O75604 1/20 0.37
RAB9A P51151 1/20 0.37
CREBBP Q92793 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4394640 0.84 GAA (0.51) MAPTTSHRALDH1A1KDM4EPOLB
SCHEMBL4392652 0.77 MAPT (0.39) MAPTTSHRALDH1A1HSD17B10KDM4E
SCHEMBL9484167 0.76 GAA (0.46) TSHRALDH1A1HSD17B10POLBHPGD
SCHEMBL9558883 0.76 CA1 (0.55) TSHRALDH1A1HSD17B10POLBHPGD
SCHEMBL10913509 0.76 CA2 (0.40) MAPTTSHRALDH1A1HSD17B10KDM4E
SCHEMBL2912444 0.75 CTDSP1 (0.47) MAPTTSHRALDH1A1HSD17B10KDM4E
SCHEMBL8780081 0.74 ALDH1A1 (0.43) MAPTTSHRALDH1A1HSD17B10KDM4E
SCHEMBL9809482 0.73 HSD17B10 (0.37) MAPTTSHRALDH1A1HSD17B10KDM4E
SCHEMBL11652672 0.72 MAPT (0.52) MAPTALDH1A1HSD17B10KDM4EMEN1
SCHEMBL6371564 0.72 GAA (0.55) MAPTALDH1A1HSD17B10KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411090-B1 Monoazo reactive red dyestuff EVERLIGHT USA INC (US) 2009-11-25 EP disclosed
CN-1257233-C Monoazo Reactive Red Dye EVERLIGHT CHEM IND CORP (CN) 2006-05-24 CN disclosed
US-6815536-B2 DYESTUFFS FOR DYEING AND PRINTING OF MATERIALS CONTAINING EITHER CELLULOSE FIBERS, SUCH AS COTTON, ARTIFICIAL COTTON, LINEN, AND ARTIFICIAL LINEN, OR SYNTHETIC POLYAMIDE, SUCH AS WOOL, SILK, AND NYLON ETC. EVERLIGHT USA, INC. 2004-11-09 US disclosed
US-20040087780-A1 Monoazo reactive red dyestuff EVERLIGHT USA, INC. 2004-05-06 US disclosed
CN-1493623-A Monoazo Reactive Red Dye 台湾永光化学工业股份有限公司 2004-05-05 CN disclosed
EP-1411090-A1 Monoazo reactive red dyestuff Everlight USA, Inc. (US) 2004-04-21 EP disclosed
EP-0777703-B1 DICYCLIC METAL COMPLEX FORMAZAN DERIVATIVES, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME AND DYEING PROCESS EMPLOYING THE SAME KYUNGIN SYNTHETIC CORP (KR) 2003-06-25 EP disclosed
US-6407220-B1 FOR DYEING AND PRINTING OF MATERIALS CONTAINING CELLULOSE FIBERS; HIGH FIXATION AND GOOD BUILD-UP EVERLIGHT USA, INC. 2002-06-18 US disclosed
US-5858026-A EXCELLENT DYEING PROPERTIES COMPARED TO THE TRICYCLIC METAL FORMAZAN COMPOUNDS; POST-DYEING SUNLIGHT AND WASHFASTNESS KYUNG-IN SYNTHETIC CORPORATION (KR) 1999-01-12 US disclosed