Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462759 | 0.83 | MEN1 (0.64) | MEN1KMT2ATBXA2RALDH1A1PRMT1 | |
| SCHEMBL9754552 | 0.82 | MEN1 (0.84) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL10463393 | 0.82 | MEN1 (0.63) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL9483898 | 0.82 | MEN1 (0.56) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL9129518 | 0.81 | MEN1 (0.69) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL9484249 | 0.81 | MEN1 (0.65) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL9485070 | 0.80 | HTT (0.56) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL13972873 | 0.79 | MEN1 (0.66) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL9485978 | 0.78 | KMT2A (0.52) | MEN1KMT2ATBXA2RALDH1A1LMNA | |
| SCHEMBL28897034 | 0.78 | ALDH1A1 (0.84) | MEN1KMT2ATBXA2RALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |