Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | LSS | P48449 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463393 | 0.86 | MEN1 (0.63) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL9021038 | 0.84 | LSS (0.65) | MEN1KMT2APRMT1LSSALDH1A1 | |
| SCHEMBL9754552 | 0.83 | MEN1 (0.84) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL10462759 | 0.82 | MEN1 (0.64) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL9493082 | 0.81 | MEN1 (0.64) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL9484173 | 0.81 | MEN1 (0.60) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL9485370 | 0.80 | MEN1 (0.58) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL9129518 | 0.80 | MEN1 (0.69) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL6974335 | 0.79 | MEN1 (0.78) | MEN1KMT2ATBXA2RPRMT1LSS | |
| SCHEMBL28897034 | 0.79 | ALDH1A1 (0.84) | MEN1KMT2ATBXA2RPRMT1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |