Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084505 | 0.88 | LMNA (0.50) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6099487 | 0.87 | TSHR (0.48) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL31518345 | 0.87 | TSHR (0.48) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29525981 | 0.82 | TSHR (0.47) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4789895 | 0.81 | HTR2C (0.57) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22832713 | 0.81 | MAPK14 (0.50) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6738366 | 0.80 | TSHR (0.76) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27569483 | 0.79 | TSHR (0.61) | TSHRLMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9122080 | 0.79 | APP (0.50) | LMNAMAPTALDH1A1ACHETDP1 | |
| SCHEMBL31398127 | 0.79 | SLC6A4 (0.55) | TSHRMAPTNPC1RAB9AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210339-A | Nitrating agent, anhydride, clay, solvent | THE DOW CHEMICAL COMPANY (US) | 1993-05-11 | — | — | US | disclosed |