Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518345 | 1.00 | TSHR (0.48) | TSHRLMNAKMT2ASLC6A4SMN1; SMN2 | |
| SCHEMBL9084505 | 0.95 | LMNA (0.50) | TSHRLMNAKMT2ASLC6A4SMN1; SMN2 | |
| SCHEMBL9484185 | 0.87 | TSHR (0.55) | TSHRLMNAKMT2ASLC6A4SMN1; SMN2 | |
| SCHEMBL2650048 | 0.82 | MAPT (0.46) | LMNAKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2727443 | 0.78 | CYP19A1 (0.54) | TSHRLMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL27569483 | 0.78 | TSHR (0.61) | TSHRLMNAKMT2ASLC6A4SMN1; SMN2 | |
| SCHEMBL2573156 | 0.76 | THRB (0.49) | LMNAKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17736221 | 0.76 | TDP1 (0.60) | TSHRLMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL22832713 | 0.76 | MAPK14 (0.50) | TSHRLMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL4789895 | 0.76 | HTR2C (0.57) | TSHRLMNASLC6A4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1403235-A1 | N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248983-A1 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | HRH2, CCR8, CYP2C8 | TSHR 3162/4885LMNA 3086/4885KMT2A 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.