Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.89 |
| ▸ | GAA | P10253 | 1/20 | 0.89 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.89 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103995 | 1.00 | L3MBTL1 (0.89) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL6715087 | 1.00 | L3MBTL1 (0.89) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL3267360 | 0.94 | L3MBTL1 (1.00) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL2998966 | 0.90 | L3MBTL1 (0.86) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL8375788 | 0.87 | L3MBTL1 (0.68) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL24682276 | 0.86 | L3MBTL1 (0.70) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL13647560 | 0.85 | L3MBTL1 (0.70) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL28507227 | 0.83 | GAA (0.63) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL1253291 | 0.83 | L3MBTL1 (0.75) | L3MBTL1GAATDP1ADRB2ADRB1 | |
| SCHEMBL29844427 | 0.83 | L3MBTL1 (0.75) | L3MBTL1GAATDP1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527175-A4 | 3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0527175-A1 | 3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991017149-A1 | 3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |