SCHEMBL3267360

SCHEMBL3267360

CCCCOc1ccc2ccccc2c1C=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 1.00
GAA P10253 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ADRB2 P07550 1/20 0.70
ADRB1 P08588 1/20 0.70
MAPT P10636 2/20 0.62
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
CYP2C9 P11712 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
CNR1 P21554 3/20 0.52
CNR2 P34972 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TSHR P16473 1/20 0.52
PLA2G1B P04054 1/20 0.51
HSP90AA1 P07900 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9484207 0.94 L3MBTL1 (0.89) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL5103995 0.94 L3MBTL1 (0.89) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL6715087 0.94 L3MBTL1 (0.89) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL2998966 0.92 L3MBTL1 (0.86) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL8741161 0.86 L3MBTL1 (0.76) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL29844427 0.86 L3MBTL1 (0.75) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL1253291 0.86 L3MBTL1 (0.75) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL7235632 0.83 L3MBTL1 (0.71) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL28765646 0.83 L3MBTL1 (0.71) L3MBTL1GAATDP1ADRB2ADRB1
SCHEMBL10458182 0.83 L3MBTL1 (0.71) L3MBTL1GAATDP1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110950804-A 2- (2-alkoxy phenyl) -4, 5-diphenyl imidazole compound and synthesis method and application thereof 广东省石油与精细化工研究院 2020-04-03 CN disclosed
US-8445630-B2 Polymers BASF SE (DE) 2013-05-21 US disclosed
US-8445630-B2 Polymers BASF SE (DE) 2013-05-21 US disclosed
EP-1914229-B1 NOVEL CERCOSPORAMIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2010-06-16 EP disclosed
EP-1858976-B1 NOVEL POLYMERS BASF SE (DE) 2009-10-14 EP disclosed
US-20090105447-A1 Novel Polymers UDC IRELAND LIMITED (IE) 2009-04-23 US disclosed
US-20090105447-A1 Novel Polymers UDC IRELAND LIMITED (IE) 2009-04-23 US disclosed
US-20090036492-A1 Novel Cercosporamide Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2009-02-05 US disclosed
CN-101300244-A Novel cercosporamide derivative DAIICHI SANKYO CO LTD (JP) 2008-11-05 CN disclosed
EP-1914229-A1 NOVEL CERCOSPORAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105447-A1 Novel Polymers PLEC, VIM, PUF60 L3MBTL1 3976/4885GAA 2458/4885TDP1 887/4885
US-20090036492-A1 Novel Cercosporamide Derivative GPR119, CBR3, SLC5A2 L3MBTL1 863/4885GAA 660/4885TDP1 4587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.