SCHEMBL9484209

SCHEMBL9484209

C#Cc1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 16/20 0.65
FAAH O00519 6/20 0.65
HSP90AA1 P07900 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
PKM P14618 1/20 0.54
MAPK1 P28482 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
DDAH1 O94760 1/20 0.48
BCHE P06276 1/20 0.48
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
CCR6 P51684 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95324 0.81 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL6135830 0.80 MGLL (0.68) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL941703 0.80 MGLL (0.68) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL17790931 0.77 MGLL (0.52) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL2042400 0.77 GAA (0.54) MGLLFAAH
SCHEMBL9468866 0.76 MGLL (0.64) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL28561470 0.75 MGLL (0.65) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL18897621 0.75 MGLL (0.60) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL19511560 0.74 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL21630074 0.74 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517364-A CROSSLINKING POYLMERS, DIELS-ALDER ADDITION REACTION PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US claimed
EP-0283204-B1 NOVEL SILOXANE MALEIMIDES LOCTITE CORPORATION (US) 1993-01-20 EP disclosed
US-5021518-A Noncracking, solvent resistant; adhesive, composites THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADM INISTRATION OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATIONS (US) 1991-06-04 US disclosed
US-4937356-A N-(3-ethynylphenyl)maleimide THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1990-06-26 US disclosed
US-4923997-A CURABLE LOCTITE CORPORATION (US) 1990-05-08 US disclosed
US-4889912-A Acetylene terminated aspartimides and resins therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-12-26 US disclosed
US-4861882-A Ethynyl terminated imidothioethers and resins therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1989-08-29 US disclosed
US-4806608-A Curable siloxane maleimide composition LOCTITE CORPORATION (US) 1989-02-21 US disclosed
EP-0283204-A2 Novel siloxane maleimides LOCTITE CORPORATION (US) 1988-09-21 EP disclosed
US-4528373-A Vinylacetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1985-07-09 US disclosed
US-4405519-A Di-Acetylene-terminated polyimide derivatives PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4405520-A Addition products of di-acetylene-terminated polymide derivatives and dienophiles having terminal maleimide grops PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4405521-A Addition products of di-acetylene-terminated polyimide derivatives with a polyimide having terminal ethylenic groups PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4405786-A Addition products of di-acetylene-terminated polyimide derivatives and an dienophile having ethylene groups PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US disclosed
US-4404139-A MOLDING MATERIALS PLASTICS ENGINEERING COMPANY (US) 1983-09-13 US disclosed
US-4402878-A Addition products of di-acetylene-terminated polyimide derivatives with a polyimide having terminal non-conjugated acetylene groups PLASTICS ENGINEERING COMPANY (US) 1983-09-06 US disclosed
US-4377525-A Addition products of diacetylene-terminated polyimide derivatives and a dienophile having a terminal vinyl group PLASTICS ENGINEERING COMPANY (US) 1983-03-22 US disclosed
US-4377673-A LAMINATION; MOLDING MATERIALS; CROSSLINKING PLASTICS ENGINEERING COMPANY (US) 1983-03-22 US disclosed
US-4331794-A Polymerization products of diimides having terminal diacetylene groups PLASTICS ENGINEERING COMPANY (US) 1982-05-25 US disclosed
US-4331601-A POLYIMIDE MOLDING MATERIALS PLASTICS ENGINEERING COMPANY (US) 1982-05-25 US disclosed