SCHEMBL6135830

SCHEMBL6135830

N#Cc1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.68
FAAH O00519 5/20 0.68
HSP90AA1 P07900 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
PKM P14618 1/20 0.56
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
ELANE P08246 1/20 0.55
POLB P06746 1/20 0.55
BCHE P06276 1/20 0.50
DDAH1 O94760 1/20 0.50
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
CCR6 P51684 1/20 0.48
CACNA1B Q00975 1/20 0.48
APBA1 Q02410 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10958731 0.89 MGLL (0.54) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL22862068 0.89 MGLL (0.55) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL215641 0.89 MGLL (0.54) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL10881352 0.87 DDAH1 (0.53) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL22862163 0.86 MGLL (0.50) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL95324 0.83 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL941703 0.82 MGLL (0.68) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL9484209 0.80 MGLL (0.65) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL16341407 0.79 MGLL (0.58) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL2733730 0.78 MGLL (0.42) MGLLFAAHHSP90AA1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
CN-114432301-B Covalent inhibitor derivative and application thereof in treatment of viral infection 北京大学 2024-05-31 CN disclosed
CN-114163629-B Method for alkylating carbon-hydrogen bonds of polyether, polyethylene glycol and polyether polyol chains under iron catalysis 西安交通大学 2022-09-09 CN disclosed
CN-113136239-B Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond 清华大学 2022-05-13 CN disclosed
CN-114432301-A Covalent inhibitor derivative and application thereof in treating virus infection 北京大学 2022-05-06 CN disclosed
CN-114163629-A Method for alkylating carbon-hydrogen bonds of polyether, polyethylene glycol and polyether polyol chains under iron catalysis 西安交通大学 2022-03-11 CN disclosed
CN-113563152-A Method for treating C five fraction and use of olefinic bond-containing compound 清华大学 2021-10-29 CN disclosed
CN-113136239-A Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond 清华大学 2021-07-20 CN disclosed
CN-113122315-A Method for treating ethylene tar and use of carbonyl compound containing olefinic bond 清华大学 2021-07-16 CN disclosed
CN-113024724-A Method for continuous polymerization of cracked fractions 清华大学 2021-06-25 CN disclosed
US-4684692-A Flame-retardant molded composition which incorporates a poly(styrene-CO-N-phenylmaleimide-CO-dibromostyrene) copolymer ATLANTIC RICHFIELD COMPANY (US) 1987-08-04 US disclosed
US-4668750-A Flame-retardant molded composition which incorporates a poly(styrene-co-N-phenylmaleimide-co-dibromostyrene) copolymer ATLANTIC RICHFIELD COMPANY (US) 1987-05-26 US disclosed
US-4663386-A Flame-retardant molded composition which incorporates a poly(styrene-co-N-phenylmaleimide-co-dibromostyrene)copolymer ATLANTIC RICHFIELD COMPANY (US) 1987-05-05 US disclosed
US-4661574-A SYNERGISTIC ATLANTIC RICHFIELD COMPANY (US) 1987-04-28 US disclosed
US-4625004-A Flame-retardant molded composition which incorporates a poly (styrene-CO-N-phenylmaleimide-CO-dibromostyrene copolymer ATLANTIC RICHFIELD COMPANY (US) 1986-11-25 US disclosed
US-4609711-A AND SYNERGIST ATLANTIC RICHFIELD COMPANY (US) 1986-09-02 US disclosed
EP-0190507-A1 Flame retardant molded composition which incorporates a poly (N-(bromophenyl) maleimide-co-styrene-co-N-phenylmaleimide)) copolymer ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-08-13 EP disclosed
EP-0188905-A1 Flame retardant molded composition which incorporates a poly (styrene-co-N-phenylmaleimide-co-dibromostyrene) ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-07-30 EP disclosed
EP-0143508-A2 Additive for water-base drilling fluid and process ATLANTIC RICHFIELD COMPANY (US) 1985-06-05 EP disclosed
US-4132715-A ISOMERIZATION OF AN ISOIMIDE CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed