Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405022 | 0.87 | DRD4 (0.57) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL31232789 | 0.87 | DRD4 (0.57) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL7432176 | 0.86 | KMT2A (0.65) | LTA4HMAPTALDH1A1HTTTSHR | |
| SCHEMBL7433993 | 0.86 | KMT2A (0.65) | LTA4HMAPTALDH1A1HTTTSHR | |
| SCHEMBL9483656 | 0.85 | TSHR (0.48) | MAPTALDH1A1HTTLMNATSHR | |
| SCHEMBL9483472 | 0.83 | DRD4 (0.55) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9483326 | 0.79 | DRD4 (0.50) | MAPTALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL12259197 | 0.79 | MAPT (0.76) | MAPTALDH1A1LMNATSHRRAB9A | |
| SCHEMBL31232798 | 0.79 | SIGMAR1 (0.59) | MAPTALDH1A1HTR7KMT2AMEN1 | |
| SCHEMBL9483370 | 0.77 | MAPT (0.56) | MAPTALDH1A1HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |