Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484584 | 0.83 | YAP1 (0.57) | ITGB3ITGA2BPOLB | |
| SCHEMBL7361850 | 0.81 | CTRB1 (0.64) | ITGB3ITGA2BCTRB1CTSLCTSK | |
| SCHEMBL7361852 | 0.81 | CTRB1 (0.64) | ITGB3ITGA2BCTRB1CTSLCTSK | |
| SCHEMBL14069202 | 0.81 | CTRB1 (0.60) | ALDH1A1ITGB3ITGA2BCTRB1POLB | |
| SCHEMBL7398976 | 0.81 | CTRB1 (0.60) | ALDH1A1ITGB3ITGA2BCTRB1POLB | |
| SCHEMBL7398974 | 0.81 | CTRB1 (0.60) | ALDH1A1ITGB3ITGA2BCTRB1POLB | |
| SCHEMBL19043611 | 0.81 | ITGB3 (0.56) | ALDH1A1LMNAITGB3ITGA2BCTRB1 | |
| SCHEMBL7301416 | 0.79 | CTRB1 (0.64) | ITGB3ITGA2BCTRB1 | |
| SCHEMBL9484576 | 0.79 | CTRB1 (0.64) | ITGB3ITGA2BCTRB1 | |
| SCHEMBL9483693 | 0.78 | CTRB1 (0.62) | ITGB3ITGA2BCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |