Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484631 | 0.85 | P2RX7 (0.59) | P2RX7CTSLCTSSKMT2A | |
| SCHEMBL9484626 | 0.85 | P2RX7 (0.59) | P2RX7CTSLCTSSKMT2A | |
| SCHEMBL30674897 | 0.84 | PPARA (0.50) | P2RX7CTSLBACE1OPRK1 | |
| SCHEMBL30674918 | 0.84 | CTSL (0.47) | P2RX7CTSLBACE1OPRK1 | |
| SCHEMBL31219188 | 0.84 | CTSL (0.47) | P2RX7CTSLBACE1OPRK1 | |
| SCHEMBL4971715 | 0.83 | MEN1 (0.49) | ATMSYKCTSLBACE1CA1 | |
| SCHEMBL4971702 | 0.83 | MEN1 (0.49) | ATMSYKCTSLBACE1CA1 | |
| SCHEMBL272157 | 0.83 | ATM (0.64) | ATMSYKCTSLCTSSKMT2A | |
| SCHEMBL30757694 | 0.82 | ATM (0.60) | ATMSYKCTSLOPRK1CTSS | |
| SCHEMBL31404216 | 0.82 | ATM (0.60) | ATMSYKCTSLOPRK1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |