Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302028 | 0.79 | RXRA (0.39) | RXRARXRBRXRG | |
| SCHEMBL9483271 | 0.75 | RXRA (0.41) | RXRARXRBRXRG | |
| SCHEMBL6330023 | 0.75 | RXRA (0.48) | RXRARXRBRXRGPRKCD | |
| SCHEMBL5706327 | 0.75 | RXRA (0.51) | RXRARXRBRXRGPRKCD | |
| SCHEMBL6666115 | 0.75 | RXRA (0.48) | RXRARXRBRXRGPRKCD | |
| SCHEMBL8670377 | 0.73 | RXRA (0.38) | RXRARXRBRXRG | |
| SCHEMBL6086554 | 0.72 | RXRA (0.46) | RXRARXRBRXRG | |
| SCHEMBL26606993 | 0.71 | RXRA (0.51) | RXRARXRBRXRGPRKCD | |
| SCHEMBL8458498 | 0.71 | RXRA (0.63) | RXRARXRBRXRG | |
| SCHEMBL8308844 | 0.71 | RXRA (0.43) | RXRARXRBRXRGPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256694-A | For skin disorders; carcinomas | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5126371-A | Precancerous skin conditions, acne, psoriasis | BASF AKTEINGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| US-4994489-A | Ester derivatives of diarylacetylenes, their compositions and their use in acne treatment | BASF AKTIENGESELLSCHAFT | 1991-02-19 | — | — | US | disclosed |
| US-4806558-A | Diarylacetylenes and their use in treating acne | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |